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AXONE

financed

Closed

Commercial multiple electrode lead technology for cardiac disease

Heart failure affects more than 14 million people in Europe, and is projected to affect about 30 million people by 2020. While the effects of Cardiac Resynchronization Therapy on the wider heart failure population are impressive,... see more

31/12/2020

LIVANOVA

4M€

Project Budget: 4M€

Project leader

SORIN CRM SAS No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

PARTICIPATION DEPralty Sin fecha límite de participación.

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Financing granted El organismo H2020 notifico la concesión del proyecto The day 2020-12-31

FTIPilot-01-2016: Fast Track to Innovation Pilot Specific Challenge:Innovation is fostered when new ideas can emerge and easily translate into socio-...

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characteristics of the participant

Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

Private Information

No hay información privada compartida para este proyecto. Habla con el coordinador.

5 Participantes

LIVANOVA

1.37M€ | Leader

EXPORTACION DE MERCANCIAS EX...

236.57K€ | participant

HERAEUS

537.69K€ | participant

UNIVERSITEIT MAASTRICHT

358.13K€ | participant

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Project duration: 47 months Date Start: 2017-01-20
End date: 2020-12-31

Project leader

SORIN CRM SAS No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Project Budget 4M€

participation deadline Sin fecha límite de participación.

Project description Heart failure affects more than 14 million people in Europe, and is projected to affect about 30 million people by 2020. While the effects of Cardiac Resynchronization Therapy on the wider heart failure population are impressive, benefits at the individual level vary considerably. Depending on the definition, the responder rate CRT is positive in 50-70% of patients, leaving 30-50% without any significant effect. This project will finalise the development of a pacemaker cardiac lead that is 5 times smaller diameter than the state-of-the-art, and start the commercialisation of the product. The project will directly improve the efficiency of Cardiac Resynchronization Therapy (CRT) by reducing the time required for the implantation procedure by 25%, and decrease the yearly healthcare costs by 82 M€/year in Europe. In addition, the project will help European companies to compete in the pacemaker market currently dominated by US companies. Axone IS4 lead combines the advantages of a single lead, which is easy to place in any coronary vein, with the capability to stimulate the left ventricle at 2 widely spaced sites for a more global resynchronization – this has previously required 2 leads to be placed in the heart. The objective of the AXONE project is to: • Finalize product industrialization • Confirm chronic pre-clinical performance with large scale studies • Perform an acute clinical study and a chronic clinical validation • Manufacture clinical and commercial products • Build the marketing plan and prepare the product launch • File CE marking of the class III medical device system • Launch the commercialization of AXONE system and start selling the system in Europe This novel approach of multi-site pacing has the potential to become the next CRT therapy device generation, initiated in Europe. This project will give an opportunity to generates 90 M€ direct revenues sales in 2026.

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