MECHPREDPRO
Financiado
Cellular mechanisms of predictive processing and its effects on perception
Predictive processing is a leading theory of brain function. However, despite several conjectures it is unknown how predictive processing is implemented at the neural level. We will try to understand the exact role of the computat...
Predictive processing is a leading theory of brain function. However, despite several conjectures it is unknown how predictive processing is implemented at the neural level. We will try to understand the exact role of the computations of the layer 5 pyramidal (L5p) cells within the framework of predictive processing. The experimental paradigm and the computational model used here are designed to answer, whether L5p cells carry predictions, as the theory of predictive processing suggests, or are they responsible for some other computation. To this end we will a) adapt experimental paradigms used with humans to study probabilistic computations in the mouse model, b) measure the dendritic input and somatic output of L5p cells in mice, c) capture this activity with computational models and d) manipulate the apical dendritic input and somatic output of L5p through noradrenaline antagonists. The project allows us to understand the mechanisms underlying predictions and their effect on perception.
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Duración del proyecto: 28 meses
Fecha Inicio: 2018-03-26
Fecha Fin: 2020-07-31
Fecha Fin: 2020-07-31
Línea de financiación: concedida
El organismo H2020 notifico la concesión del proyecto el día 2020-07-31
Línea de financiación objetivo
El proyecto se financió a través de la siguiente ayuda:
MSCA-IF-2017:
Individual Fellowships
Cerrada
hace 7 años
Presupuesto
El presupuesto total del proyecto asciende a
171K€
Líder del proyecto
HUMBOLDTUNIVERSITAET ZU BERLIN
No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico
TRL
4-5
Perfil tecnológico
TRL
4-5
398.47K€ |
Participante