Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

ReverseParalysis

Financiado

BRAIN-SPINE INTERFACES TO REVERSE UPPER- AND LOWER-LIMB PARALYSIS

A spinal cord injury (SCI) alters the communication between the brain and spinal cord. The consequences are dramatic impairments of upper-limb and lower-limb motor functions, which have a profound impact on the affected person, th... ver más

30/04/2025

ONWARD MEDICAL

2M€

Presupuesto del proyecto: 2M€

Líder del proyecto

ONWARD MEDICAL NV No se ha especificado una descripción o un objeto social para esta compañía.

Ver 6 Participantes

Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2022-03-17

HORIZON-EIC-2021-TRANSITIONCHALLENGES-01-01: Medical Technology and Devices: fro... Scope:EU-funded early-stage Research on novel Medical Technologies and Devices is uncovering unique...

I+D

Cerrada hace 3 años

0% 100% 100%

6 Participantes

ONWARD MEDICAL

1.23M€ | Lider

swiss aeropole SA

N.D. | Participante

CEA

1.07M€ | Participante

DTS PATENT UND RECHTSANWALTE...

96.00K€ | Participante

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Proyectos interesantes

GRASPAGAIN A Direct Sensorimotor Connection with the Spared Neural Code... 1M€ Cerrado

DPI2017-91117-EXP REHABILITACION MOTORA DE LA LESION MEDULAR MEDIANTE APLICACI... 61K€ Cerrado

DPI2015-69098-REDT RED TEMATICA DE INVESTIGACION EN NEUROTECNOLOGIAS PARA LA AS... 35K€ Cerrado

PID2021-124111OB-C32 DISEÑO DE ESTRATEGIAS DE ESTIMULACION ESPINAL TRANSCUTANEA P... 161K€ Cerrado

SpiLearn Characterization of spinal learning in a repetitive yet skil... 176K€ Cerrado

PID2021-124111OB-C31 DESARROLLO DE UNA INTERFAZ NEURAL-MAQUINA AUTO-CALIBRADA PAR... 226K€ Cerrado

Duración del proyecto: 37 meses Fecha Inicio: 2022-03-17
Fecha Fin: 2025-04-30

Líder del proyecto

ONWARD MEDICAL NV No se ha especificado una descripción o un objeto social para esta compañía.

Presupuesto del proyecto 2M€

Descripción del proyecto A spinal cord injury (SCI) alters the communication between the brain and spinal cord. The consequences are dramatic impairments of upper-limb and lower-limb motor functions, which have a profound impact on the affected person, their family, and society. Currently, there are no approved therapies for SCI. The resulting costs of care amount to more than 2.5 M? over the lifetime of a person with SCI. Two ERCs combined with two ERC-PoCs enabled us to prototype two brain-spine interfaces (BSIs) that link the intended movements decoded from motor cortex activity to precise electrical stimulations of the spinal cord to promote these movements. These BSIs restored walking and arm/hand movements in nonhuman primate models of SCI, and as we report here, enabled one patient with chronic paralysis to walk again outdoors. These prototypes were partly based on repurposed devices that were not optimized for the intended applications, and thus presented shortcomings. Here, we propose to integrate two breakthrough technologies to develop two fully-implantable BSIs that will remedy these limitations. The first technology consists of the only existing fully-implantable neurosensor for wireless monitoring of cortical activity in humans based on high-density grids positioned over the dura mater. The second technology is the only implantable neurostimulation system dedicated to the recovery of movement after paralysis. This system combines an implantable pulse generator that enables highly reliable, real-time control of spinal cord stimulation, and a portfolio of electrode arrays that have been designed to leverage the mechanisms through which this stimulation restores movement. Two small scale clinical trials will demonstrate that these BSIs restore lower-limb and upper-limb movements in humans with chronic paralysis. These studies will provide specifications for industrial versions of the BSIs, opening the path to a commercially-viable revolution for people living with paralysis.

Conecta tu I+D

Entra hoy

¿Olvide mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores