BRAIN ACTUATED SPINAL CORD STIMULATION TO RESTORE GAIT AFTER PARALYSIS
Spinal cord injury (SCI) leads to severe motor impairments that significantly alter the quality of life of affected people and incur substantial cost for families and society. The ideas developed within the framework of our ERC st...
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Información proyecto BRAINGAIT
Duración del proyecto: 21 meses
Fecha Inicio: 2019-11-27
Fecha Fin: 2021-08-31
Fecha límite de participación
Sin fecha límite de participación.
Descripción del proyecto
Spinal cord injury (SCI) leads to severe motor impairments that significantly alter the quality of life of affected people and incur substantial cost for families and society. The ideas developed within the framework of our ERC starting and Consolidator grants led to the development of neurotechnologies that restored walking in paralyzed individuals. This treatment involves the delivery of targeted electrical spinal cord stimulation protocols that reactivate the spinal cord below the injury and amplify the residual commands from the brain. Crucial to the recovery of voluntary movements is the temporal coincidence between the location of the stimulation and the residual command from the brain. To achieve a perfect synchronization, we directly linked decoding of motor intention from brain recordings to the modulation of spinal cord stimulation protocols. We validated the therapeutic efficacy of this wireless brain-spine interface in a nonhuman primate model of SCI. Here, we aim to establish the technical and regulatory feasibility of this wireless brain-spine interface in humans, develop additional intellectual property, and prepare the path to the commercialization of this revolutionary neurotechnology.