Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

TARGET SLEEP

Financiado

Cerrado

Boosting motor learning through sleep and targeted memory reactivation in ageing...

Boosting motor learning through sleep and targeted memory reactivation in ageing and Parkinson s disease Rehabilitation is an important therapeutic strategy for patients with Parkinson’s disease (PD), whereby motor adaptations are learned to maintain daily functioning. However, patients often present difficulty consolidating newly le... ver más

31/12/2021

KU Leuven

166K€

Presupuesto del proyecto: 166K€

Líder del proyecto

KATHOLIEKE UNIVERSITEIT LEUVEN No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2021-12-31

MSCA-IF-2018: Individual Fellowships

I+D

Cerrada hace 6 años

0% 100% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

1 Participantes

KU Leuven

166.32K€ | Lider

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Proyectos interesantes

CLASSy Aging Closed Loop Acoustic Stimulation during Sleep to enhance mot... 166K€ Cerrado

PSI2012-32441 CAMBIOS CEREBRALES ESTRUCTURALES Y FUNCIONALES ASOCIADOS A L... 53K€ Cerrado

NeMoRe NeuroModulation Rehabilitation. A neurofeedback and transcra... 165K€ Cerrado

PSI2010-15024 REACTIVACION NEURONAL COMO MECANISMO CRITICO DE LA MEMORIA E... 103K€ Cerrado

MotMotLearn Motivating Motor Learning The Role of Reward Punishment an... 1M€ Cerrado

PSI2015-67285-R IMPLEMENTACION DE UN PROGRAMA DE REHABILITACION COGNITIVA EN... 46K€ Cerrado

Duración del proyecto: 29 meses Fecha Inicio: 2019-07-23
Fecha Fin: 2021-12-31

Líder del proyecto

KATHOLIEKE UNIVERSITEIT LEUVEN No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 166K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Rehabilitation is an important therapeutic strategy for patients with Parkinson’s disease (PD), whereby motor adaptations are learned to maintain daily functioning. However, patients often present difficulty consolidating newly learned skills into long-term memory, which reduces the benefits of training. Interventions that enhance consolidation are therefore projected to diminish the impact of PD. Sleep facilitates motor memory consolidation in healthy adults, especially in combination with targeted memory reactivation (TMR). TMR works by adding associated auditory stimuli during learning, which are replayed during sleep and thus reinforce the recently formed neural connections. Importantly, recent work has suggested that consolidation during sleep may be preserved in PD, but robust findings are lacking and have not involved TMR. This knowledge gap is astonishing given the potential benefits that can be gained by integrating sleep interventions into rehabilitation. My objective is to address this imperative by investigating the effect of sleep on motor memory consolidation by experimentally manipulating exposure to sleep and TMR for the first time. Concretely, I will compare the effect of a 2-hour daytime nap with or without TMR to that of a wake control period in PD and age-matched controls. I will use a validated motor sequence task to test for behavioral markers of motor learning and apply state-of-the-art neuroimaging techniques to study the imprint of neural network changes underlying consolidation. My training objectives include teaching and supervising students in rehabilitation–related neuroscientific topics and research leadership development. I will also implement a rigorous dissemination and communication plan to achieve optimal societal impact of my research findings. I anticipate my MSCA to spark new sleep interventions that boost the effectiveness of rehabilitation and improve the wellbeing of our ageing population, in particular those affected by PD.

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores