Innovating Works

BioArchitecture

Financiado
Bioprinting Complex Tissue mimicking Architectures
Over the past ten years, 3D bioprinting has emerged as a powerful tool to fabricate human tissue models ex vivo. These models can be used for drug discovery, to obtain a better understanding of physiological and pathological mecha... Over the past ten years, 3D bioprinting has emerged as a powerful tool to fabricate human tissue models ex vivo. These models can be used for drug discovery, to obtain a better understanding of physiological and pathological mechanisms, and in the future to replace diseased or injured tissues and organs. To successfully fabricate functional tissues, 3D bioprinted constructs should emulate the anatomical features of the native tissue’s extracellular matrix (ECM). However, current bioprinting technologies can neither mimic the nano- and microscale fibrillar ECM, nor replicate the anisotropic and spatially organized architecture and gradients of complex tissues, such as cartilage, cornea, and the heart. Within BioArchitecture, we aim to develop a novel 3D bioprinter platform, capable of bioprinting hierarchical and organized biomaterial constructs at high resolution to instruct and guide cell growth and tissue maturation. The BioArchitecture platform will allow researchers and pharmaceutical companies to perform better drugs target identification in native-like bioprinted human tissues ex vivo, which will better predict the efficacy and safety of the tested drugs and significantly decrease healthcare costs by reducing the required amount of personnel, infrastructure, an animal experiments associated to a new drug development. ver más
31/01/2023
DWI LEIBNIZINSTITU...
150K€
Duración del proyecto: 27 meses Fecha Inicio: 2020-10-15
Fecha Fin: 2023-01-31

Línea de financiación: concedida

El organismo H2020 notifico la concesión del proyecto el día 2023-01-31
Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:
ERC-2020-POC: Call for proposals for ERC Proof of Concept Grant
Cerrada hace 4 años
Presupuesto El presupuesto total del proyecto asciende a 150K€
Líder del proyecto
DWI LEIBNIZINSTITUT FUR INTERAKTIVE MATERIALI... No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico TRL 4-5