Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

BePolGen

Financiado

Cerrado

Behaviour Pollutants and Genomics exploring their interactions in a fish model

Aquatic habitats are increasingly exposed to chemicals that, even at low levels, can disturb the endocrinology of organisms. These endocrine disrupting chemicals (EDCs) can have severe impacts on reproductive physiology, yet knowl... ver más

31/05/2015

GCU

231K€

Presupuesto del proyecto: 231K€

Líder del proyecto

THE GLASGOW CALEDONIAN UNIVERSITY No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Financiación concedida El organismo FP7 notifico la concesión del proyecto el día 2015-05-31 No tenemos la información de la convocatoria

0% 100% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

1 Participantes

GCU

0.00€ | Lider

Proyectos interesantes

BES-2013-064041

Environmental S...

Medical Technol...

84K€ Cerrado

CTM2012-37547

Environmental S...

Medical Technol...

137K€ Cerrado

ETAA

Environmental S...

Medical Technol...

100K€ Cerrado

REEF

Environmental S...

Medical Technol...

4M€ Cerrado

EDCSANTIANDROGENS

Environmental S...

Medical Technol...

172K€ Cerrado

EpiSTOX

Environmental S...

Medical Technol...

170K€ Cerrado

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Líder del proyecto

THE GLASGOW CALEDONIAN UNIVERSITY No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 231K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Aquatic habitats are increasingly exposed to chemicals that, even at low levels, can disturb the endocrinology of organisms. These endocrine disrupting chemicals (EDCs) can have severe impacts on reproductive physiology, yet knowledge of their effects on evolutionary processes and population viability is fundamentally lacking. Using the invasive mosquitofish Gambusia holbrooki, the Fellow will use behavioural and genetic assays to reveal how EDCs impact reproductive success and sexual selection. This study will be the first to examine the effects of EDCs on both female and male reproductive behaviour and quality of offspring. Crucially, in a novel approach, cutting-edge, Next Generation Sequencing (NGS) will be used to explore EDC-induced changes in gene expression in the Central Nervous System. The Fellow will expose mosquitofish to 17α-ethynyl estradiol (EE2), a synthetic estrogen used in oral contraceptive pills, and experimentally determine how exposure affects fish reproductive behaviour, reproductive success and gene expression. The Fellow will establish transcriptomic profiles of the fish brain, ovary or testis with NGS and use digital transcriptomics to analyse the effects of EE2 exposure on gene expression. The identity and extent of change of the differentially expressed transcripts will be interpreted with respect to the observed behavioural changes. This study will deepen our knowledge on the genetics of how organisms adapt to human-induced environmental changes and provide evidence on how genome and environment interact. The joint programme of research and training will allow the Fellow to use her existing expertise in behavioural ecotoxicology and critically to engage with new techniques. The programme will give the Fellow competencies in research-related activities and state-of-the-art NGS and bioinformatics that are essential to her in becoming an independent scientist able to command her own research funding and supervise a research team.

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores