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ARON

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Assay Ready Organ Network

In drug development, there is an urgent need for more physiological and predictive pre-clinical in-vitro assays to test the efficacy and toxicity of compounds. This to allow new medicines to be brought to the market quicker and sa... see more

30/06/2020

INSPHERO

71K€

Project Budget: 71K€

Project leader

INSPHERO AG No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

PARTICIPATION DEPralty Sin fecha límite de participación.

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Financing granted El organismo H2020 notifico la concesión del proyecto The day 2020-06-30

EIC-SMEInst-2018-2020: SME instrument

I+D

Cerrada does 5 years

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characteristics of the participant

Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

Private Information

No hay información privada compartida para este proyecto. Habla con el coordinador.

2 Participantes

INSPHERO

50.00K€ | Leader

PIGRA ENGINEERING

254.64K€ | participant

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Project duration: 6 months Date Start: 2019-12-06
End date: 2020-06-30

Project leader

INSPHERO AG No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Project Budget 71K€

participation deadline Sin fecha límite de participación.

Project description In drug development, there is an urgent need for more physiological and predictive pre-clinical in-vitro assays to test the efficacy and toxicity of compounds. This to allow new medicines to be brought to the market quicker and safer. With the growing biological complexity of today’s diseases, it is vital to have interconnected 3D tissue structures of multiple organs in order to investigate biological cross-talk. Today, such physiological and predictive pre-clinical in-vitro assays are not available. Here, InSphero presents ARON, their Assay-Ready Organ Network, to address the urgent need for more physiological and predictive pre-clinical in-vitro assays and aims to study the feasibility of a successful market introduction. ARON is the most advanced modular in-vitro assay platform and will set a new standard for a wide range of cell-based pre-clinical testing by shifting the organ-on-a-chip technology from a late-stage, luxury service to routinely used ready-to-use assays. This enables pharma and biotech companies to develop drugs in a faster and more efficient way, without the use of animals. All elements and process steps guarantee routine implementation for everyone, while experimental complexity is minimized. ARON has the unique option that the consumables are assay-ready, directly shipped on-site, on-demand, and worldwide. InSphero is a leading supplier of organotypic in-vitro 3D microtissues for predictive drug testing and has grown yearly by 40% in the past years. ARON will turn today's service possibilities into a scalable product and will enable to offer assays for highly competitive pricing. The (USA dominated) 3D tissue market is expected to grow with CAGR of 63% to reach a market size of 1.5 billion EUR in 2024. A successful market introduction will impact the EU’s society and economy by creating hundreds of jobs, accelerating drug development that will improve the health of EU-citizens, while reducing cost, time-to-market and the need for animal testing

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