AURORA
Financiado
Applying photon Up-conversion in ROtaxanes for super-Resolution microscopy Analy...
This multidisciplinary AURORA project focuses on the development of prototype rotaxane (molecular ring-on-thread) structures displaying triplet fusion upconversion photoprocess. Structural design will instill this process via spon...
This multidisciplinary AURORA project focuses on the development of prototype rotaxane (molecular ring-on-thread) structures displaying triplet fusion upconversion photoprocess. Structural design will instill this process via spontaneous excited dye collisions in confined trajectories of the designed interlocked molecules to create a fluorescent state (from two combined low energy photons). Such architectures will help to collect information on molecular photon upconversion and intramolecular diffusion processes through time-resolved spectroscopies. Moreover, it will produce intermittent fluorescence blinking by which detailed analysis will afford a new methodology for super-resolution imaging, namely below the diffraction limit of light. In theory this can provide solutions to some limitations of actual approaches and impact this research field. Fluorescence modulation within these autonomous [2]rotaxanes by triplet fusion will lead to studies down to the single-molecule level (based on Stochastic Optical Reconstruction Microscopy) which will be employed to establish a new localization microscopy method (T2-STORM) and be validated through imaging commercial nanostructured biomacromolecules.
Both leading French research institutes, Institut des Sciences Moleculaires (ISM) and Laboratoire Photonique Numerique et Nanosciences (LP2N) will co-host the AURORA project. The French fellow, specialist in synthetic organic and supramolecular chemistry, will be taught molecular photophysics/photochemistry and super-resolution fluorescence imaging. Additional work packages will guarantee efficient scientific advances, training, career development, management, communication and potentially technology transfer. Association of the fellow and research groups skills at the chemistry-photophysics-imaging interface, available infrastructure and equipment, will participate to both the fellow’s future independent research career and achieving ambitious AURORA objectives.
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Duración del proyecto: 26 meses
Fecha Inicio: 2023-07-06
Fecha Fin: 2025-09-30
Fecha Fin: 2025-09-30
Línea de financiación: concedida
El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2023-07-06
Línea de financiación objetivo
El proyecto se financió a través de la siguiente ayuda:
HORIZON-MSCA-2022-PF-01-01:
MSCA Postdoctoral Fellowships 2022
Cerrada
hace 2 años
Presupuesto
El presupuesto total del proyecto asciende a
196K€
Líder del proyecto
UNIVERSITE DE BORDEAUX
No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico
TRL
4-5
Perfil tecnológico
TRL
4-5