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Application of a New Kinetic Microbial Theory-Microbial Transition State- on Enr...

Application of a New Kinetic Microbial Theory-Microbial Transition State- on Enriched Nitrifying Activated Sludge Model Traditional engineering models known as Activated Sludge Model (ASM) are commonly used for operation, design, and optimization of wastewater treatment plants. ASM predict microbial growth with simulation and calibration of model p... ver más

31/12/2024

ITU

148K€

Presupuesto del proyecto: 148K€

Líder del proyecto

ISTANBUL TEKNIK UNIVERSITESI No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2024-12-31

HORIZON-WIDERA-2022-TALENTS-02-01: Fostering balanced brain circulatio... ExpectedOutcome:This action builds on the MSCA Postdoctoral Fellowships 2021 action (HORIZON-MSCA-PF...

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1 Participantes

ITU

148.48K€ | Lider

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Duración del proyecto: 26 meses Fecha Inicio: 2022-10-13
Fecha Fin: 2024-12-31

Líder del proyecto

ISTANBUL TEKNIK UNIVERSITESI No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 148K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Traditional engineering models known as Activated Sludge Model (ASM) are commonly used for operation, design, and optimization of wastewater treatment plants. ASM predict microbial growth with simulation and calibration of model parameters which are bound to a range of experimental conditions. Recently, Microbial Transition State (MTS) approach was proposed which is a statistical-physics based theory of microbial growth linking thermodynamic balances and growth rates. A growth equation was derived from these first principles, which links a flux (the growth of microbes) to a force, i.e. the Gibbs free potential energy density in medium contained in randomly distributed substrate molecules. MTS has not been fully verified with experimental data on mixed microbial cultures such as sustained in wastewater treatment systems. As the theory is developed for describing standard microbial growth, conditions such as inhibition of growth by any pollutant compound has not been considered/applied in real systems. The aim of the research is to investigate growth kinetics of two different nitrifying bacteria individually (Ammonia and Nitrite oxidizers) with MTS modeling approach and identify nitirification growth kinetics. Inhibition of bacterial growth with different types of inhibitors will also be investigated in order to evaluate and verify application of MTS model for different guilds in mixed microbial cultures under different environmental conditions. The outcomes of the study will contribute to understanding and control of microbial growth processes in engineered and natural treatment systems. Identification of inhibition kinetics will be used for mitigation of pollution generated from industrial processes as well as theoretical development of MTS theory to be applied in more complex biological process applications. The project is an intersection of environmental engineering, molecular biology, and modeling disciplines which will contribute Green Deal Strategy of EU.

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