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Advanced bioinformatics for genome and metagenome analyses and discovery of nove...

Advanced bioinformatics for genome and metagenome analyses and discovery of novel biocatalists from extremophiles implications for improving industrial bioprocesses The aim of this proposal is to acquire new insights about the mechanisms of environmental adaptation, particularly for cold-adapted organisms, and to discover novel metabolic pathways and enzymes with potential industrial value. W... ver más

30/11/2018

UNICAM

338K€

Presupuesto del proyecto: 338K€

Líder del proyecto

UNIVERSITA DEGLI STUDI DI CAMERINO No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Ver 9 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2018-11-30

Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:

MSCA-RISE-2014: Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE)

I+D

Cerrada hace 10 años

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9 Participantes

UNICAM

81.00K€ | Lider

EKIN S COOP

233.62K€ | Participante

EPI

130.50K€ | Participante

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Duración del proyecto: 48 meses Fecha Inicio: 2014-11-28
Fecha Fin: 2018-11-30

Líder del proyecto

UNIVERSITA DEGLI STUDI DI CAMERINO

TRL 4-5

Presupuesto del proyecto 338K€

Descripción del proyecto The aim of this proposal is to acquire new insights about the mechanisms of environmental adaptation, particularly for cold-adapted organisms, and to discover novel metabolic pathways and enzymes with potential industrial value. We intend to accomplish this goal by establishing a collaboration and a knowledge-exchange network between industrial and academic partners aiming at developing bioinformatic tools for genomic analysis and biotechnology tools for directed evolution. The partners present high complementarity: UNICAM holds genomic sequences from psychrophilic and mesophilic ciliates that need to be annotated and analysed. Sabanci provides environmental samples for the isolation and characterization of new extremophiles. CAMBRIDGE provides the know-how for the discovery of new metabolic pathways valuable for understanding environmental adaptation. BMR Genomics and COMSATS possess all the facilities for genome sequencing and annotation and bioinformatic expertise with the purpose of developing new tools to analyse genomes of microorganisms from extreme environment. UNIMIB owns the facilities for the heterologous expression of gene sequences in bacteria and yeasts and technologies to assess and implement the properties of novel enzymes towards industrial application. We are confident that the establishment of the international research network proposed, with its synergistic effects, will significantly contribute to push all the involved laboratories to the top level in the field of production of active biomolecules and in the discovery of mechanisms of molecular adaptation under extreme environmental conditions. These discoveries may help the manufacturing of a new generation of ordinary facilities, as cleaning agents, biofuels, with a significant impact on the everyday life of European citizens.

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