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NeuroLang

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Accelerating Neuroscience Research by Unifying Knowledge Representation and Anal...

Accelerating Neuroscience Research by Unifying Knowledge Representation and Analysis Through a Domain Specific Language Neuroscience is at an inflection point. The 150-year old cortical specialization paradigm, in which cortical brain areas have a distinct set of functions, is experiencing an unprecedented momentum with over 1000 articles being pub... see more

29/02/2024

INRIA

1M€

Project Budget: 1M€

Project leader

INSTITUT NATIONAL DE RECHERCHE EN INFORMATIQU... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

PARTICIPATION DEPralty Sin fecha límite de participación.

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Financing granted El organismo H2020 notifico la concesión del proyecto The day 2024-02-29

ERC-2017-STG: ERC Starting Grant Scope:Objectives

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2 Participantes

INRIA

1.50M€ | Leader

FARELL INSTRUMENTS

189.81K€ | participant

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Project duration: 75 months Date Start: 2017-11-17
End date: 2024-02-29

Project leader

INSTITUT NATIONAL DE RECHERCHE EN INFORMATIQU... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Project Budget 1M€

participation deadline Sin fecha límite de participación.

Project description Neuroscience is at an inflection point. The 150-year old cortical specialization paradigm, in which cortical brain areas have a distinct set of functions, is experiencing an unprecedented momentum with over 1000 articles being published every year. However, this paradigm is reaching its limits. Recent studies show that current approaches to atlas brain areas, like relative location, cellular population type, or connectivity, are not enough on their own to characterize a cortical area and its function unequivocally. This hinders the reproducibility and advancement of neuroscience. Neuroscience is thus in dire need of a universal standard to specify neuroanatomy and function: a novel formal language allowing neuroscientists to simultaneously specify tissue characteristics, relative location, known function and connectional topology for the unequivocal identification of a given brain region. The vision of NeuroLang is that a unified formal language for neuroanatomy will boost our understanding of the brain. By defining brain regions, networks, and cognitive tasks through a set of formal criteria, researchers will be able to synthesize and integrate data within and across diverse studies. NeuroLang will accelerate the development of neuroscience by providing a way to evaluate anatomical specificity, test current theories, and develop new hypotheses. NeuroLang will lead to a new generation of computational tools for neuroscience research. In doing so, we will be shedding a novel light onto neurological research and possibly disease treatment and palliative care. Our project complements current developments in large multimodal studies across different databases. This project will bring the power of Domain Specific Languages to neuroscience research, driving the field towards a new paradigm articulating classical neuroanatomy with current statistical and machine learning-based approaches.

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