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RadioClick

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A versatile ultrafast Click platform for antibody based radio diagnostics

Diagnosing cancer as early as possible is one of the most powerful strategies in modern medicine to improve human well-being. Antibodies (Abs) are excellent molecules that can be used to target specific tumors. As Abs require hour... see more

30/11/2019

JOHANNES GUTENBERG...

150K€

Project Budget: 150K€

Project leader

JOHANNES GUTENBERGUNIVERSITAT MAINZ No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

PARTICIPATION DEPralty Sin fecha límite de participación.

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Financing granted El organismo H2020 notifico la concesión del proyecto The day 2019-11-30

ERC-2017-PoC: ERC-Proof of Concept Scope:Scope:

I+D

Cerrada does 8 years

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characteristics of the participant

Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

Private Information

No hay información privada compartida para este proyecto. Habla con el coordinador.

4 Participantes

JOHANNES GUTENBERGUNIVERSITA...

87.50K€ | Leader

ORTIZ CONSTRUCCIONES Y PROYE...

205.52K€ | participant

EMBL

62.50K€ | participant

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Project duration: 18 months Date Start: 2018-05-15
End date: 2019-11-30

Project leader

JOHANNES GUTENBERGUNIVERSITAT MAINZ No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Project Budget 150K€

participation deadline Sin fecha límite de participación.

Project description Diagnosing cancer as early as possible is one of the most powerful strategies in modern medicine to improve human well-being. Antibodies (Abs) are excellent molecules that can be used to target specific tumors. As Abs require hours to days for accumulating on tumor surfaces, the use of Abs for nuclear imaging (such as PET imaging) is limited by the short half-lives of popular radioisotopes. Therefore, we plan to move the step of radiolabeling from the bench to the tumor itself. However, the entanglement of Abs with an artificial chemical probe is one of the most promising but at the same time one of the most technically challenging developmental areas in biotechnology. Our unique approach is based on the production of hybrid-Abs, which combine in only one click step the power of synthetic chemistry with the best of biology (custom-biologics). Our unique selling points are ultra-fast, exceptional bioorthogonal and specific labeling reactions in living organism as well as a both-sided modularity of the connection between Abs and chemical probe. By doing so, high contrast visualization of the cancer will become possible.

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