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NanoPilot

Financiado

Cerrado

A Pilot Plant for the Production of Polymer based Nanopharmaceuticals in Complia...

A Pilot Plant for the Production of Polymer based Nanopharmaceuticals in Compliance with GMP The aim of NanoPilot will be to set-up a flexible and adaptable pilot plant operating under GMP for the production of small batches of polymer-based nanopharmaceuticals, which exhibit significant potential in the field of drug-del... ver más

30/06/2019

CIDETEC

6M€

Presupuesto del proyecto: 6M€

Líder del proyecto

FUNDACION CIDETEC No se ha especificado una descripción o un objeto social para esta compañía.

TRL 2-3 | 14M€

Fecha límite participación Sin fecha límite de participación.

Ver 11 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2019-06-30

NMP-08-2014: Scale-up of nanopharmaceuticals pro... Scope:Specific challenge: In nanomedicine the scale-up of nanopharmaceuticals production from pre-cl...

I+D

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Características del participante

Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

11 Participantes

CIDETEC

2.05M€ | Lider

SYLENTIS

643.12K€ | Participante

Chemtrix

586.45K€ | Participante

CANOE

670.75K€ | Participante

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Duración del proyecto: 54 meses Fecha Inicio: 2014-12-15
Fecha Fin: 2019-06-30

Líder del proyecto

FUNDACION CIDETEC No se ha especificado una descripción o un objeto social para esta compañía.

TRL 2-3 | 14M€

Presupuesto del proyecto 6M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto The aim of NanoPilot will be to set-up a flexible and adaptable pilot plant operating under GMP for the production of small batches of polymer-based nanopharmaceuticals, which exhibit significant potential in the field of drug-delivery particularly for the design of second-generation nanopharmaceuticals. Three different processes will be established for the production of three different nanopharmaceuticals selected on the basis of their TRL and positive commercial evaluation: a) topical treatment of ocular pain associated with dry eye syndrome containing short interfering RNA and lactic acid, b) A resuspendable HIV nanovaccine for intranasal vaccination containing 12 peptides in its formulation. c) Hyaluronan based hollow spheres intended for intravesical instillation, for the treatment of interstitial cystitis/painful bladder syndrome. State of the art production processes including micro reactors and highly advanced characterization techniques will ensure the quality of the nanodrugs. Existing laboratories suitable for large-scale production of biologics in compliance with GMP, and owned by the coordinator, will be adapted and certified within this project to enable the operability of the pilot plant. NanoPilot consists of nine complementary partners composed by 1 Industry and 2 academia developers of the nanosystems to scale-up. A research Institute expert in nanoparticle characterizacion and already operating in compliance with Good laboratory practices. An SME and an Industry that will develop ad-hoc continuous flow reactors for the optimization of two of the three processes. A consultancy (SME) expert in Quality system implementation and laboratory information management systems. A second consultancy (SME) in charge of the business plan, that will also help the coordinator in dissemination and exploitation activities. Finally, a research centre with a recorded track in nanomedicine, already operating under ISO 9001, and will be in charge of the pilot plant.

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