Innovating Works

NanoPilot

Financiado
A Pilot Plant for the Production of Polymer based Nanopharmaceuticals in Complia...
A Pilot Plant for the Production of Polymer based Nanopharmaceuticals in Compliance with GMP The aim of NanoPilot will be to set-up a flexible and adaptable pilot plant operating under GMP for the production of small batches of polymer-based nanopharmaceuticals, which exhibit significant potential in the field of drug-del... The aim of NanoPilot will be to set-up a flexible and adaptable pilot plant operating under GMP for the production of small batches of polymer-based nanopharmaceuticals, which exhibit significant potential in the field of drug-delivery particularly for the design of second-generation nanopharmaceuticals. Three different processes will be established for the production of three different nanopharmaceuticals selected on the basis of their TRL and positive commercial evaluation: a) topical treatment of ocular pain associated with dry eye syndrome containing short interfering RNA and lactic acid, b) A resuspendable HIV nanovaccine for intranasal vaccination containing 12 peptides in its formulation. c) Hyaluronan based hollow spheres intended for intravesical instillation, for the treatment of interstitial cystitis/painful bladder syndrome. State of the art production processes including micro reactors and highly advanced characterization techniques will ensure the quality of the nanodrugs. Existing laboratories suitable for large-scale production of biologics in compliance with GMP, and owned by the coordinator, will be adapted and certified within this project to enable the operability of the pilot plant. NanoPilot consists of nine complementary partners composed by 1 Industry and 2 academia developers of the nanosystems to scale-up. A research Institute expert in nanoparticle characterizacion and already operating in compliance with Good laboratory practices. An SME and an Industry that will develop ad-hoc continuous flow reactors for the optimization of two of the three processes. A consultancy (SME) expert in Quality system implementation and laboratory information management systems. A second consultancy (SME) in charge of the business plan, that will also help the coordinator in dissemination and exploitation activities. Finally, a research centre with a recorded track in nanomedicine, already operating under ISO 9001, and will be in charge of the pilot plant. ver más
30/06/2019
CIDETEC
6M€
Duración del proyecto: 54 meses Fecha Inicio: 2014-12-15
Fecha Fin: 2019-06-30

Línea de financiación: concedida

El organismo H2020 notifico la concesión del proyecto el día 2019-06-30
Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:
NMP-08-2014: Scale-up of nanopharmaceuticals production
Cerrada hace 10 años
Presupuesto El presupuesto total del proyecto asciende a 6M€
Líder del proyecto
FUNDACION CIDETEC No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico TRL 2-3 14M