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MUSCLEGUY

Financiado

A novel muscle disorders 3D in vitro system for drug screening and validation.

MUSCLEGUY represents a unique opportunity to commercialize a novel 3D in vitro system for screening and validation of drug candidates to treat muscle disorders. Although skeletal muscle disorders are relatively rare they pose a hu... ver más

31/03/2018

iMM

150K€

Presupuesto del proyecto: 150K€

Líder del proyecto

INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANT... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Ver 2 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2018-03-31

ERC-PoC-2015: ERC Proof of Concept Grant

I+D

Cerrada hace 9 años

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2 Participantes

iMM

150.00K€ | Lider

SELENA IBERIA

587.10K€ | Participante

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Duración del proyecto: 21 meses Fecha Inicio: 2016-06-14
Fecha Fin: 2018-03-31

Líder del proyecto

INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANT... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 150K€

Descripción del proyecto MUSCLEGUY represents a unique opportunity to commercialize a novel 3D in vitro system for screening and validation of drug candidates to treat muscle disorders. Although skeletal muscle disorders are relatively rare they pose a huge socioeconomic burden. Currently there is a lack of therapeutic options for the majority of patients. This is, for an important part, due to the lack of reliable, reproducible, and physiological relevant in vitro models of muscle disorders that accurately reflect the in vivo reality on which novel therapeutic strategies may be developed. We generated a novel 3D in vitro system of highly matured myofibers, the relevant functional unit of the muscle affected in most muscle disorders and used it to identify novel therapeutic targets of muscle disorders. During MUSCLEGUY, we will further technically optimise our in vitro system to generate human relevant disease models for muscle disorder. Such systems can be used for drug screening and validation. In addition, we will further investigate the commercial feasibility of our product by conducting an elaborate market analysis and establishing a strong IP portfolio. The ultimate aim of MUSCLEGUY is to develop a business plan to convince the relevant stakeholders. Our novel 3D in vitro system for muscle disorder has the potential to meet the requirements for pharmaceutical drug discovery research (HTS format, reproducible and robust) and drastically reduce the associated costs and the number of animals used, in order to further increase the interest of the pharmaceutical industry for muscle disorders.

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