MUSCLEGUY
Financiado
A novel muscle disorders 3D in vitro system for drug screening and validation.
MUSCLEGUY represents a unique opportunity to commercialize a novel 3D in vitro system for screening and validation of drug candidates to treat muscle disorders. Although skeletal muscle disorders are relatively rare they pose a hu...
MUSCLEGUY represents a unique opportunity to commercialize a novel 3D in vitro system for screening and validation of drug candidates to treat muscle disorders. Although skeletal muscle disorders are relatively rare they pose a huge socioeconomic burden. Currently there is a lack of therapeutic options for the majority of patients. This is, for an important part, due to the lack of reliable, reproducible, and physiological relevant in vitro models of muscle disorders that accurately reflect the in vivo reality on which novel therapeutic strategies may be developed.
We generated a novel 3D in vitro system of highly matured myofibers, the relevant functional unit of the muscle affected in most muscle disorders and used it to identify novel therapeutic targets of muscle disorders. During MUSCLEGUY, we will further technically optimise our in vitro system to generate human relevant disease models for muscle disorder. Such systems can be used for drug screening and validation. In addition, we will further investigate the commercial feasibility of our product by conducting an elaborate market analysis and establishing a strong IP portfolio. The ultimate aim of MUSCLEGUY is to develop a business plan to convince the relevant stakeholders. Our novel 3D in vitro system for muscle disorder has the potential to meet the requirements for pharmaceutical drug discovery research (HTS format, reproducible and robust) and drastically reduce the associated costs and the number of animals used, in order to further increase the interest of the pharmaceutical industry for muscle disorders.
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Duración del proyecto: 21 meses
Fecha Inicio: 2016-06-14
Fecha Fin: 2018-03-31
Fecha Fin: 2018-03-31
Línea de financiación: concedida
El organismo H2020 notifico la concesión del proyecto el día 2018-03-31
Línea de financiación objetivo
El proyecto se financió a través de la siguiente ayuda:
ERC-PoC-2015:
ERC Proof of Concept Grant
Cerrada
hace 9 años
Presupuesto
El presupuesto total del proyecto asciende a
150K€
Líder del proyecto
INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANT...
No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico
TRL
4-5
Perfil tecnológico
TRL
4-5
587.10K€ |
Participante