Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

SKIN-CANCER-PROBE

Financiado

Cerrado

A novel handheld probe coupled to mass spectrometer as a non invasive tool for f...

A novel handheld probe coupled to mass spectrometer as a non invasive tool for fast in vivo diagnosis of skin cancer Ambient mass spectrometry (AMS) has gained substantial attention in numerous research fields including clinical diagnosis as being a nondestructive, fast and simple approach. Despite of the advances in mass spectrometry (MS) one o... ver más

02/04/2023

METU

145K€

Presupuesto del proyecto: 145K€

Líder del proyecto

MIDDLE EAST TECHNICAL UNIVERSITY No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2023-04-02

MSCA-IF-2019: Individual Fellowships

I+D

Cerrada hace 5 años

0% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

1 Participantes

METU

145.36K€ | Lider

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Proyectos interesantes

HEMOSPEC Advanced spectroscopic hemogram for personalized care agains... 5M€ Cerrado

DERMAE Clinical research for the validation of a non invasive medic... 71K€ Cerrado

PID2020-119326RA-I00 ANALYSIS POINT-OF-CARE EN MUESTRAS MINIMAMENTE INVASIVAS EMP... 56K€ Cerrado

BIOplasma Use flexible Tube Micro Plasma F TP for Lipidomics 163K€ Cerrado

ARIADNE Redefining mass spectrometry a breakthrough platform for r... 4M€ Cerrado

SmartGuide Smart Biopsy Tool for Real Time Cancerous Cell Characterizat... 3M€ Cerrado

Duración del proyecto: 36 meses Fecha Inicio: 2020-04-01
Fecha Fin: 2023-04-02

Líder del proyecto

MIDDLE EAST TECHNICAL UNIVERSITY No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 145K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Ambient mass spectrometry (AMS) has gained substantial attention in numerous research fields including clinical diagnosis as being a nondestructive, fast and simple approach. Despite of the advances in mass spectrometry (MS) one of its main disadvantages is the simultaneous introduction of the matrix and analyte to MS that results in low sensitivity associated with a high background and ion suppression, and frequent instrumental maintenance. Therefore, there is a need for a ground-breaking sampling tool that is combinable with MS and that does not compromise the above mentioned merits. Here we propose (i) to develop a novel handheld probe, which will have micro extraction mechanism for small molecules/biomarkers from the surface and can be combined with MS for real time targeted and untargeted analyses; (ii) to utilize the probe as a clinical diagnostic tool for noninvasive fast determination of skin cancer. The probe will be designed as a surface touch sampling device suitable for spot analysis and for continuous mode chemical imaging of surface. The device will be integrated with online desorption using a solvent junction and desorbed metabolites will be directed to MS. As proof-of-concept, skin cancer biomarkers and some other typical skin metabolites will be targeted during the probe development. Preliminary analyses with the probe will be conducted on the surface of agarose gel spiked with the selected metabolites mimicking artificial skin surface using MS in targeted mode. Upon development of the probe and prove of the detection of the biomarkers from the synthetic skin media the study will be extended to in vivo mice model with tumor. This novel probe will make a significant impact as rapid and reliable diagnostic tool. This project will open an opportunity for the researcher to develop her future career by implementing the novel probe in emerging research fields (e.g. clinical, forensic, etc.), where fast and reliable analytical tools are in high demand.

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores