A 3D bioprinting platform with exchangeable tailor made print heads to engineer...
A 3D bioprinting platform with exchangeable tailor made print heads to engineer tissue surrogates
Three-dimensional (3D) bioprinting has been projected as one of the technologies with higher prospects to engineer tissue surrogates, which are i) an unquestionable demand for regenerative medicine and ii) an acknowledged upgrade...
ver más
31/08/2022
UMINHO
150K€
Presupuesto del proyecto: 150K€
Líder del proyecto
UNIVERSIDADE DO MINHO
No se ha especificado una descripción o un objeto social para esta compañía.
TRL
4-5
Fecha límite participación
Sin fecha límite de participación.
Financiación
concedida
El organismo H2020 notifico la concesión del proyecto
el día 2022-08-31
¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video
Información proyecto BioPrint4All
Duración del proyecto: 29 meses
Fecha Inicio: 2020-03-19
Fecha Fin: 2022-08-31
Líder del proyecto
UNIVERSIDADE DO MINHO
No se ha especificado una descripción o un objeto social para esta compañía.
TRL
4-5
Presupuesto del proyecto
150K€
Fecha límite de participación
Sin fecha límite de participación.
Descripción del proyecto
Three-dimensional (3D) bioprinting has been projected as one of the technologies with higher prospects to engineer tissue surrogates, which are i) an unquestionable demand for regenerative medicine and ii) an acknowledged upgrade of 2D in vitro cultures as reliable and predictive testing/screening systems for pharma and cosmetic industries. Despite the important milestones achieved so far, bioprinting functional tissues surrogates has proved difficult. The biggest challenge still is the fabrication of complex (different cell types and extracellular components) structures that work, as a whole, as in the native tissue, thus being physiologically relevant.
The key 3D bioprinting elements are the printer – more specifically the printing head – and the bioinks (live cells plus extracellular components). As the print head controls the deposition of the bioink, one cannot be dissociated from the other. Thus, the successful 3D bioprinting of functional tissue surrogates is directly linked to the possibility to have a 3D printer that supports the characteristics of each bioink designed explicitly for each compartment of a specific tissue. Therefore, a new mind-set in which an integrated development of the print heads (guaranteeing processability and cell-friendly conditions) and the bioinks (ideal combination of biomaterial and cell designed explicitly for each compartment of a specific tissue) is required.
This project proposes to prove the feasibility of having an on-demand 3D printing platform that can combine multiple print heads with different features, virtually at any combination. This strategy will foster reaching significant milestones in a shorter time and expectably at lower costs due to more straightforward and highly innovative scientifically-driven approaches.