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PULSE

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3D Printing of Ultra-fideLity tissues using Space for anti-ageing solutions on E...

Bioprinting in Space is one of the novel promising and perspective research directions in the rapidly emerging field of biofabrication. There are several advantages of bioprinting in Space. First, under the conditions of micrograv... ver más

31/03/2028

UNIVERSITEIT MAAST...

4M€

Presupuesto del proyecto: 4M€

Líder del proyecto

UNIVERSITEIT MAASTRICHT No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

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Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2023-04-01

Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:

HORIZON-EIC-2022-PATHFINDEROPEN-01-01: EIC Pathfinder Open 2022

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UNIVERSITEIT MAASTRICHT

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Últimas noticias

27-11-2024: DGIPYME En las últimas 48 horas el Organismo DGIPYME ha otorgado 1 concesiones

27-11-2024: FUNDACION-EOI En las últimas 48 horas el Organismo FUNDACION EOI ha otorgado 2 concesiones

25-11-2024: ECE En las últimas 48 horas el Organismo ECE ha otorgado 52 concesiones

Duración del proyecto: 59 meses Fecha Inicio: 2023-04-01
Fecha Fin: 2028-03-31

Líder del proyecto

UNIVERSITEIT MAASTRICHT

TRL 4-5

Presupuesto del proyecto 4M€

Descripción del proyecto Bioprinting in Space is one of the novel promising and perspective research directions in the rapidly emerging field of biofabrication. There are several advantages of bioprinting in Space. First, under the conditions of microgravity, it is possible to bioprint constructs employing more fluidic channels and, thus, more biocompatible bio-inks. Second, microgravity conditions enable 3D bioprinting of tissue and organ constructs of more complex geometries with voids, cavities, and tunnels. Third, a novel scaffold-free, label-free, and nozzle-free technology based on multi-levitation principles can be implemented under the condition of microgravity. The ideal Space bioprinters must be safe, automated, compact, and user friendly. Thus, there are no doubts that systematic exploration of 3D bioprinting in Space will advance biofabrication and bioprinting technology per se. Vice versa 3D bioprinted tissues could be used to study pathophysiological biological phenomena when exposed to microgravity and cosmic radiation that will be useful on Earth to understand ageing conditioning of tissues, and in space for the crew of deep space manned missions. In PULSE, we aim at developing a radical new bioprinting technology based on multiple levitation principles and to use Space as an accelerator of ageing on Earth. As a proof of concept study, we will use this newly developed bioprinting technology to create cardiac 3D in vitro models able to better mimic cardiac physiology compared to organoids. We will use such models to study cardiac ageing and test the efficacy of antiinflammatory/ anti-oxidative drugs with anti-ageing potential.

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