H2020
Europeo
ExpectedOutcome:Successful proposals will contribute to the impacts of this destination and the European policies it supports, in particular the European Green Deal, the circular economy action plan and the bioeconomy strategy, They should help improve European industrial[1] sustainability, competitiveness and resource independence by developing innovative bio-based products. They should engage all stakeholders and improve their knowledge and understanding of science, in particular of biotechnology-based value chains, and increase benefits for consumers.
Project results should contribute to all of the following expected outcomes:
Lower production costs, improved safety and access to final efficient, specific, high-yield and high-value, climate-neutral circular applications[2]Lower dependence on land-based production systems, minimising the risk of Indirect Land Use Change (ILUC)[3], with specific technical solutions and strategies for innovative, high-output, multi-source high-value contained applications, based on a variety of biological organisms[4] and their cultivation systems and technologies involved. Methodologically robust verification of sustaina...
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ExpectedOutcome:Successful proposals will contribute to the impacts of this destination and the European policies it supports, in particular the European Green Deal, the circular economy action plan and the bioeconomy strategy, They should help improve European industrial[1] sustainability, competitiveness and resource independence by developing innovative bio-based products. They should engage all stakeholders and improve their knowledge and understanding of science, in particular of biotechnology-based value chains, and increase benefits for consumers.
Project results should contribute to all of the following expected outcomes:
Lower production costs, improved safety and access to final efficient, specific, high-yield and high-value, climate-neutral circular applications[2]Lower dependence on land-based production systems, minimising the risk of Indirect Land Use Change (ILUC)[3], with specific technical solutions and strategies for innovative, high-output, multi-source high-value contained applications, based on a variety of biological organisms[4] and their cultivation systems and technologies involved. Methodologically robust verification of sustainability of the production system via life-cycle assessment approaches. This covers the greater resource efficiency of production pathways, by applying the upcycling and cascading use of biomass residues or side-streams.More mature and advanced biotechnology solutions for the innovative culture, screening and processing of the selected organisms, as well as the related digital applications, thus contributing to European industrial competitiveness. Higher engagement of SMEs, for creating skilled jobs and bringing other socio-economic benefits for end users and/or patients, through expanding the range of natural ingredients for new applications in industrial sectors, enhancing the functional performance of the investigated value chains and products, and contributing to more sustainable industrial practices and resource independence of the EU Member States and associated countries.Better public understanding across EU Member States and associated countries of biotechnology, and of biodiversity conservation and enhancement objectives set out in the EU biodiversity strategy and respect for the principles of access and benefit sharing (UN Biodiversity Convention), via clear, inclusive and transparent communication strategies. International cooperation is encouraged, to allow the exchange of best practice, while ensuring win-win scenarios and contributing to European competitiveness.
Scope:The innovative bioeconomy sectors need to diversify and deliver technological and industrial solutions based on available and sustainably sourced biomass. In particular, this covers sustainable application in various industrial systems for high value products and uses, such as in the pharmaceutical, diagnostic and veterinary sectors[5], especially in the context of biorefining and other (industrial) high-value uses[6].
This calls for identifying, optimising, screening and monitoring of the growing conditions in suitable systems such as bioreactors[7], from where they need to be efficiently processed, extracted and converted into industrial outputs of interest. The scope covers innovative multi-scale bioreactor designs, and related innovations such as hydroponics systems and phenotyping platforms for increased sustainability of biomass production, and its efficient, pathogen-free processing and use.
Where relevant, proposals should seek links with and capitalise on the results of past and ongoing research projects (under Horizon 2020 and other EU-funded initiatives). Proposals should:
Develop bio-based production platforms applying resource-efficient principles (ensuring savings on water, energy, chemical inputs, biomass side-streams or residues), including the study of mixed multi-species communities, and applying modern biotechnological principles, as well as efficient separation and extraction approaches for products of interest.Identify and implement the best combination of appropriate technical solutions and practices for specific industrial value chains (justifying the choice, including on business viability), as well as the barriers and drivers derived from governance and market aspects, while seeking engagement and understanding of all actors. Participation of industry and SMEs is considered essential. Develop and transparently communicate: (i) the key parameters to monitor and measure the qualitative and quantitative impacts of these solutions and practices for different optimization and production systems, (ii) the potential of replacing available traditional alternatives, if relevant, and trade-offs, including with respect to biodiversity, patient perspective, and (iii) the associated improvement of socio-economic resilience of the businesses for the jobs creation and industrial competitiveness. Develop and test mechanisms involving all actors and specifically including the research community and bio-based industries in knowledge co-creation, exchange, feedback and communication to demonstrate and accompany all actors (e.g. civil society including patient and other related groups) to implement and understand of solutions for improved bio-based products and processes and to address other environmental impacts. Develop specific recommendations for policy makers, while seeking involvement of broader civil society.Consider contribute data and results to the European Commission’s Knowledge Centre for Bioeconomy hosted by the JRC. For this topic, it is not mandatory to integrate the gender dimension (sex and gender analysis) into research and innovation.
Specific Topic Conditions:Activities are expected to achieve TRL 7 by the end of the project – see General Annex B.
Cross-cutting Priorities:International Cooperation
[1]In connection with European partnerships under Cluster 6, in particular Circular Bio-based Europe (CBE).
[2]e.g. production of engineered proteins such as reagents, diagnostics, innovative (e.g. scalable plant-based) vaccines or metabolites for specific industrial products (pharmaceuticals, veterinary products, biological reagents)
[3]As defined by the recast Renewable Energy Directive(EU) 2018/2001 from December 2018, and Land use and forestry regulation for 2021-203, see https://ec.europa.eu/clima/policies/forests/lulucf_en
[4]Such as algae, fungi, plant cells, invertebrates, microorganisms, including complex multi-species communities. See a complementary topic HORIZON-CL6-2021-CIRCBIO-01-05: Novel non-plant feedstocks for industrial applications
[5]e.g. antibodies, vaccines, proteins, peptides, bioactive metabolites, linking with Horizon Europe Cluster 1 Health and topic HORIZON-CL6-2021-CIRCBIO-01-05: Novel non-plant feedstocks for industrial applications
[6]e.g. cosmetics, food ingredients
[7]The proposals should cover size of the chosen contained systems, to enable upscaling and replication.
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